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New Products


HALO Glycan LC Column for Oligosaccharides, Protein linked Glycans & Glycopeptides

A  new column line in the HALO BioClass family – HALO Glycan columns.

HALO Glycan LC Columns for oligosaccharides, including protein-linked glycans and glycopeptides

 

The HALO Glycan stationary phase is a highly polar ligand that possesses 5 hydroxyl groups tethered to the 2.7-micron Fused-Core silica via novel proprietary linkage chemistry.

The Fused-Core particle used for HALO Glycan has a surface area of ~ 135 m
2/g and an average pore size of 90Å. 

This high performance material provides a column that is specifically targeted for separations of oligosaccharides and particularly protein-linked glycans and glycopeptides by hydrophilic interactive liquid chromatography (HILIC).

 

This latest column introduction joins the existing BioClass column family giving you a wide range of application-specific solutions to separations for bio-derived samples. Each lot of Glycan packing material is tested for Quality Assurance by separation of a procainamide-reducing end- labeled glycan ladder of oligosaccharides of 2-25 glucose units (GU). See the attached example QA chromatogram. The peaks for 5 and 10 GU must meet tight specifications for retention and peak widths before the lot is approved for Glycan columns. The QA chromatogram for the lot of material used for manufacture of each Glycan column is included in the box with every column.

The attached Application Note demonstrates a suggested protocol for the high efficiency separations
of N-Glycans using a HALO Glycan column.

 The list of specifications and utilities for all BioClass columns is shown , CLICK HERE

  HALO BioClass Glycan Columns
Part # Description
92922-405 BioClass Glycan, 2.7 μm, 2.1 x 50 mm
92922-605 BioClass Glycan, 2.7 μm, 2.1 x 100 mm
92922-705 BioClass Glycan, 2.7 μm, 2.1 x 150 mm
92924-405 BioClass Glycan, 2.7 μm, 4.6 x 50 mm
92924-605 BioClass Glycan, 2.7 μm, 4.6 x 100 mm
92924-705 BioClass Glycan, 2.7 μm, 4.6 x 150 mm
92922-105 BioClass Glycan,Guard Columns, 2.1 x 5 mm (3/pk)
92924-105 BioClass Glycan,Guard Columns, 4.6 x 5 mm (3/pk)

No competitor has more phases on superficially porous particles designed specifically for bioseparations than does HALO.

Contact Achrom +32 9 3800647 or send email to achrom@achrom.be for prices and delivery time.

 

 
toegevoegd op 26-01-2017 om 19:35




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